What is hCG (Human Chorionic Gonadotrophin)?

hCG is a hormone which is produced by cells in the placenta by women during pregnancy. It is a hormone that supports the normal development of an egg in a woman’s ovaries, and stimulates the release of the egg during ovulation.

To use it as a medicine, hCG is either extracted from the urine of pregnant women or produced from cultures of genetically modified cells using recombinant DNA technology.

What is hCG used for?

hCG is used to stimulate ovulation and to treat infertility in women, and to increase sperm count in men.

Men who are on Testosterone Replacement Therapy (TRT) sometimes take hCG to restore the size of their testicles to their pre-TRT level, and to increase their fertility if they are planning to have children in the near future (read about this in our fertility article here).

Human Chorionic Gonadotrophin is also used in young boys when their testicles have not dropped down into the scrotum normally, or when puberty is delayed.

Why is hCG out of stock in the UK at the moment? Has hCG been discontinued?

hCG in the UK has mostly been available from UK pharmacies as Pregnyl 1500IU from Merck Sharp & Dohme Limited (MSD).

It is a prescription only medicine, so you must have a prescription from your doctor to buy it.

However, recently Pregnyl 1500IU has been out of stock in pharmacies across the UK – so what is going on?

We spoke to our pharmacy, and they informed us that Pregnyl has been discontinued by MSD – Pregnyl is no longer available in the UK.

Update: we now have access to Gonassi HCG 5000IU which our partner doctors can prescribe!

What are the alternatives if Pregnyl hCG is no longer available?

There are other companies who manufacture and distribute hCG under different brand names, including:

Some of these options are a bit more expensive than Pregnyl, so at OptiMale we decided to look at alternative medicines that might deliver the same benefits to our male patients as hCG.

After consulting with our doctors and our pharmacy, we are investigating and testing Clomid Clomifene Citrate to see if it is a viable alternative.

We will publish our results soon.

Clomid Clomifene Citrate

In the meantime, contact us for more information on how to get treatment with Gonassi HCG or with your questions: