Nebido - Testosterone injection

The most convenient way to take testosterone – just 1 injection every 8-10 weeks!

Stable blood levels

Nebido has a slow release which maintains stable blood levels.

Low injection frequency

Nebido is injected at a low frequency so you can live your life normally!

Nurse administered

Nebido can be injected by a nurse so you don’t have to.

What is Nebido used for?

Nebido is used for the treatment of low testosterone in men. It is one option for testosterone replacement therapy in men with low or no production of natural testosterone (hypogonadism).

How does Nebido work?

Nebido is a long acting injection that contains the active ingredient testosterone, which is the same as the naturally occurring male hormone testosterone. It replaces the testosterone produced in your body to ensure normal levels.

Testosterone is known as an androgen – one of the male steroidal hormones. It is produced mainly by the testicles and is the main hormone essential for normal male growth and development. It is responsible for the development of the male sex organs and male sexual characteristics. It is also very important for mood, energy levels, sexual desire and physical strength.

Testosterone in men is essential for the production of sperm, the maintenance of erectile potency, and the functioning of the prostate gland and other reproductive structures. It also has functions in the skin, muscles, skeleton, kidney, liver, bone marrow and central nervous system.

Low levels of testosterone can cause decreased sex drive, inability to achieve an erection, infertility (due to decreased sperm production), decreased mental and physical activity, fatigue and weakening of bones (osteoporosis). Nebido is given as testosterone replacement therapy when natural testosterone levels fall too low, causing the issues above.

Natural testosterone levels often fall with age and fall rapidly following surgical removal of the testicles. They also fall due to decreased functioning of the testicles (hypogonadism or eunuchoidism), or by decreased gonadotrophin production by the pituitary gland, as a result of pituitary disease. There are many reasons that men nowadays appear to have testosterone levels 20% lower than they were 20 years ago.

Testosterone replacement therapy allows testosterone levels to return to normal, thus relieving the symptoms.

Nebido is injected every 8-10 weeks to provide stable blood levels. The oil sits in the muscle and releases slowly over time. The low injection frequency allows Nebido to be injected by a health professional to avoid self injection.

Benefits of Nebido injections

  • Steady blood levels
  • Injection only every 8-10 weeks
  • Nurse administration possible for people with injection anxiety
  • No mess
  • No risk of transferring to women and children

How do I use it?

Nebido works by slowly releasing testosterone from a depot of oil left under the skin.

The injection is normally performed by a health care professional in a clinic every 8-10 weeks.

If being self-injected then safe and sterile injection protocol should be adhered to. Wash your hands with soap and water before handling the medication, syringes and needles.

Normally the lateral thigh or upper quadrant of the glute should be used as the injection site to reduce the risk of hitting major veins, arteries and nerves.

Once the needle is inserted at 90 degrees, the plunger should be pulled back slightly (aspirated) and the syringe checked for blood to ensure the oil is not injected into an artery or vein. If blood is pulled back into the syringe the needle should be removed completely and a new needle used to attempt the process in a different location.

If no blood is aspirated then the plunger should be slowly pressed to complete the injection.

A 25G or larger needle is recommended to allow passing of the viscous oil.


  • Hands should be washed with soap and water before beginning the injection process.
  • Nebido injections should only be used by the prescribed user.
  • A new, sterile needle and syringe should be used for each injection.
  • The injection should only be administered on an area sterilised with alcohol swabs.
  • The injection should only be administered into a muscle belly – not into an artery or vein.
  • The syringe should always be aspirated (the plunger pulled back to see if blood is drawn into the syringe) before the injection. If blood is drawn then the injection process should be stopped.
  • Injections should never be performed through clothing.
  • Injections should be performed on clean, dry, unbroken skin after use of sterile wipes.

Anyone taking TRT needs to have frequent blood tests to ensure optimal levels of testosterone, oestrogen and other hormones. This treatment should only be used by patients who have been assessed by a professional, GMC certified doctor. They should be deemed to have testosterone deficiency and be safe and suitable for this treatment.

If you would like more advice on Nebido or Testosterone Replacement Therapy, please contact us, we are here to help.